Tablets are the most often used solid oral dose form due to their high patient compliance, stability, simplicity of handling, and convenience of transportation. Tableting technology has come a long way over the years. Due to issues with segregation, content homogeneity, and physical stability, mixing and formulating solid dosage forms can be extremely difficult. When producing solid dosage drug products, these variables must be carefully controlled. A homogeneous and segregation-free dosage formulation must be developed, which requires careful consideration of the excipients used at each stage of the formulation and process development process. A wide range of equipment has been developed to make it easier to combine excipients with solid dose pharmaceuticals. There have been reports of several novel formulation procedures in addition to traditional methods including direct compression, wet granulation, and dry granulation. With the goal of establishing content homogeneity during the mixing and formulation of solid dosage medications, these technical innovations have enhanced the manufacture and quality of solid dose medicinal products.

This study aims to thoroughly examine the segregation techniques currently used by pharmaceutical companies in Northern India, assessing how well they comply with industry best practices and regulatory standards. By addressing and taking into consideration the factors, challenges, and limitations in the business, the author of this study examined the degree of the concerns generated by segregation in the Indian pharmaceutical sector in the context of a thorough literature analysis. The author's expertise of this subject was enhanced by earlier publications, which helped her collect the primary data for her research study. Through an investigation of challenges encountered by manufacturers during the implementation of effective segregation methods, the study aims to offer pragmatic perspectives and suggest suggestions for enhancing production procedures.

An online questionnaire survey consisting of fourteen questions was distributed to a group of pharmaceutical experts employed in various pharmaceutical organizations around Northern India in order to collect data for this study. This study highlights the various strategies incorporated in pharmaceutical manufacturing. With insights that can help with product quality, regulatory compliance, and eventually patient access to safe and effective pharmaceuticals, the expected results will have a major impact on the pharmaceutical sector in Northern India. At present, the Indian pharmaceutical industry is dedicated to enhancing its production processes through the use of measures aimed at reducing segregation. With time pharmaceutical industries have ventured to adapt innovative ideas for a better future ahead.