An Assessment of the impact of bioinformatics and artificial intelligence in vaccine development. A perspective of subject matter experts working in biopharma companies.
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Authors
Rajan, Arya
Issue Date
2023-07
Type
Thesis
Language
Keywords
Alternative Title
Abstract
Efficient vaccine development has been critical in combating the COVID-19 pandemic. The
study presented here examined the role and function of artificial Intelligence (AI) and
bioinformatics in vaccine development by the pharmaceutical sector with a main focus on the
development of vaccines for the SARS-CoV-2 virus. The study looked at the main drawbacks
and benefits of utilizing AI compared to more traditional approaches and the development of
AI to produce vaccines in the future
A total number of 11 subject matter experts from the biopharmaceutical industry took part
in the qualitative interviews via Zoom. The study's selection of samples was made using non
probability sampling techniques. Social media platforms like LinkedIn groups and Facebook
were used to reach out to participants. In terms of study philosophy, the study adhered to
pragmatism and interpretivism.
The results found that the development of vaccines has benefited greatly from the use of
artificial intelligence over conventional methods. The study explored a variety of
bioinformatics methods such as clustering, principal component analysis, and high
throughput analysis. These methods are used to detect thousands of genes at a time. The
main phases in the development of vaccines are DNA and protein sequencing. A more
affordable and effective solution to the problem was provided by bioinformatics. The
pharmaceutical industry used AI in various ways, including boosting vaccine manufacturing
and shortening and minimizing efforts to provide more accurate and safe vaccinations. Future
applications of AI in vaccine research are anticipated to result in more precise and safer
vaccinations, as well as greater market availability and vaccine production. Obstacles that
occur include data bias, privacy, and confidentiality concerns, algorithmic flaws, and ethical
dilemmas.
Overall, AI and bioinformatics have been very beneficial to the rapid development
of new vaccines. To understand how the novel variants will affect vaccine effectivity, more
research will need to be carried out using nanotechnology and other new technologies that
AI is introducing.