An Assessment of the impact of bioinformatics and artificial intelligence in vaccine development. A perspective of subject matter experts working in biopharma companies.

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Rajan, Arya
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Efficient vaccine development has been critical in combating the COVID-19 pandemic. The study presented here examined the role and function of artificial Intelligence (AI) and bioinformatics in vaccine development by the pharmaceutical sector with a main focus on the development of vaccines for the SARS-CoV-2 virus. The study looked at the main drawbacks and benefits of utilizing AI compared to more traditional approaches and the development of AI to produce vaccines in the future

A total number of 11 subject matter experts from the biopharmaceutical industry took part in the qualitative interviews via Zoom. The study's selection of samples was made using non probability sampling techniques. Social media platforms like LinkedIn groups and Facebook were used to reach out to participants. In terms of study philosophy, the study adhered to pragmatism and interpretivism.

The results found that the development of vaccines has benefited greatly from the use of artificial intelligence over conventional methods. The study explored a variety of bioinformatics methods such as clustering, principal component analysis, and high throughput analysis. These methods are used to detect thousands of genes at a time. The main phases in the development of vaccines are DNA and protein sequencing. A more affordable and effective solution to the problem was provided by bioinformatics. The pharmaceutical industry used AI in various ways, including boosting vaccine manufacturing and shortening and minimizing efforts to provide more accurate and safe vaccinations. Future applications of AI in vaccine research are anticipated to result in more precise and safer vaccinations, as well as greater market availability and vaccine production. Obstacles that occur include data bias, privacy, and confidentiality concerns, algorithmic flaws, and ethical dilemmas.

Overall, AI and bioinformatics have been very beneficial to the rapid development of new vaccines. To understand how the novel variants will affect vaccine effectivity, more research will need to be carried out using nanotechnology and other new technologies that AI is introducing.

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