The thesis aims to evaluate the impacts of post marketing surveillance on falsified medicines among healthcare professionals (medical doctors and pharmacists) and consumers in Nigeria by conducting a questionnaire-based survey for quantitative research. in order to achieve this, the awareness and knowledge of falsified medicines, factors affecting effective post marketing surveillance in Nigeria and recommendations to improve adequate post marketing surveillance of falsified medicine in Nigeria. The healthcare professionals (medical doctors and pharmacists) and consumers were evaluated to ascertain their level of awareness and knowledge of falsified medicines, healthcare professionals’ direct experiences to post marketing surveillance guidelines and frequencies of falsified medicine cases during their experience. The efficiency of Mobile Authentication Services (MAS). Sixty-six (66) respondents voluntarily participated and responded accordingly to the questionnaire structured survey.20 (30.0%) respondents were medical doctors, 24 (36.0%) respondents were pharmacists while 22 (33.0%) respondents were consumers. There was an absolute 100.0% respondents to willingness to update their knowledge about guidelines and regulations of post marketing surveillance of falsified medicine. Their most preferred method was through current guidelines from regulatory bodies. There were factors associated with inadequate impacts of post marketing surveillance which included NAFDAC regulatory policies, social economic status of the country and cost implications. Increasing awareness of falsified medicines was recommended to be implemented by continuous advertisements through internet, radios and newspapers. Designing and implementing new applicable regulations to help improve post marketing surveillance.